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Two or three species side by side, with potency shown as both a percentage and the dose that follows from it.

Psilocybe cubensisPsilocybe azurescensPsilocybe semilanceata
Common namesGolden teacher, Cube, Gold cap, San IsidroFlying saucer, Azzies, Blue angelLiberty cap, Witch's hat, Spitzkegeliger Kahlkopf
Potency tierModerateExtremeVery high
Total alkaloids0.25–1.8%1.3–2.5%0.5–2.5%
Relative to cubensis1.00×2.86×1.59×
Common dose, dried1.75–2.5 g0.61–0.88 g1.1–1.58 g
Spore printDark purple-brown to purple-blackDark purple-brownDark purple-brown
BruisingBlue to blue-green, readily, within minutesStrong, rapid, blue-blackWeak, often confined to the stem base, sometimes absent
Key characterA persistent white ring dusted dark purple-brown with fallen spores, on a stem that bruises blue.A pronounced persistent umbo, the 'flying saucer' outline, on a tough stem rooted in wood chips near the Pacific coast, with no ring.A sharply conical cap with a distinct nipple that never flattens, on a thin wavy stem, growing in grass, never on dung and never on wood.
SubstrateCattle dung, Water buffalo dung, Well-manured pastureDeciduous wood chips, Driftwood, Dune grass debris, Alder and cottonwoodNutrient-rich grassland, Sheep and cattle pasture, Lawns and playing fields
RegionsSoutheastern United States, Mexico, Central and South America, Caribbean, Southeast Asia, Australia, IndiaPacific Northwest of the United States, Coastal Oregon and Washington, Introduced to parts of northern EuropeBritain and Ireland, Scandinavia, Northern and central Europe, Pacific Northwest, New Zealand, Chile
SeasonWarm and wet months; year-round in the tropicsSeptember to January, peaking after the first hard rainsLate August to November, after cool wet weather
Cultivationbeginnerintermediateadvanced
Look-alikes2 recorded1 recorded5 recorded